Vice President, Internal Audit

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: The Vice President, Internal Audit will serve as the founding leader responsible for building, scaling, and managing the company’s internal audit function. This individual will establish the charter, framework, and methodologies required to support a growing global pharmaceutical commercial organizationally. The role reports functionally to the Audit Committee of the Board of Directors and administratively to the Chief Financial Officer. Key Responsibilities: Build, scale and lead the global internal audit function. Develop near term and long term vision for the department, including hiring plans and use of external consultants. Establish the Internal Audit Charter. Collaborate with legal and compliance functions in development and execution of periodic enterprise risk management assessments. Design, execute and lead the company’s risk-based internal audit plan and testing, mapping coverage to financial and operational vulnerabilities. Assess existing internal controls across the global organization, identify gaps and provide recommendations for strengthening control environment. Establish, evaluate, and strengthen audit methodologies, processes and programs. Collaborate with key functional heads regarding strategic changes impacting the Company’s design of processes and related internal controls. Develop communication framework with Audit Committee and Senior Management, including presenting annual risk-based audit plans and findings directly to the Audit Committee. Collaborate with compliance, finance, tax, HR, regulatory and quality functions to ensure organizational processes comply with federal, state, and local laws, and industry standards. Collaborate with legal and compliance on internal investigations, whistle-blower escalations, and other special assignments. Establish operating framework with existing SOX/ICFR team. Leverage technology, automation, data analytics, and artificial intelligence to enhance audit coverage, insight, efficiency, and overall audit quality. Leadership & Capabilities: Builder Mindset: Proven track record of launching, scaling, or heavily restructuring an internal audit function—ideally transitioning a company from pre-commercial to the global commercial stage. Trusted Advisor and Relationship Builder: Ability to partner effectively and collaboratively with finance, legal, IT, compliance, risk management, external auditors, and business leaders across the organization to operate a valued, independent risk and assurance function that supports strategic enterprise objectives. Hands-On Execution: Willingness to execute granular testing and draft documentation directly during the early building phases before the team scales. Required Skills, Experience and Education: Previous experience in leading an internal audit function. 15+ years of progressive audit experience, with at least 5 years operating within a public life science or pharma setting. CPA or CIA is required. Extensive early career experience in a Big 4 or top-tier national accounting firm serving public life science or pharma clients. #LI-JW1#LI-Remote The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy . For additional information, please contact privacy@revmed.com . Base Pay Salary Range $294,000 — $367,000 USD We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message. Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address. If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.