Senior Director, Medical Affairs, Canada

Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway. The Opportunity: Reporting to the General Manager Canada, the Medical Director, Canada is the medical leader responsible for defining and executing the local medical strategy RevMed portfolio and launches. This role serves as the medical voice within the Canadian Leadership Team, ensuring scientific excellence, compliant medical engagement, and strong alignment between global strategy and local patient, physician, and healthcare system needs. This leader will ensure that Canadian medical considerations are embedded in the regional medical strategy and plans and will partner with the General Manager and crossfunctional teams, as well as the Global Medical Affairs leadership team. The incumbent will contribute to building the Candian medical team and work closely with the Global and Regional Medical Affairs teams across Med Affairs functions. Act as the Medical Affairs lead for Canada, accountable for local medical strategy, execution, and impact across the oncology portfolio. Translate global medical and clinical strategies into locally relevant medical plans aligned with country regulations and clinical practice. Build and maintain strong relationships with national and regional key opinion leaders, oncology networks, academic institutions, and scientific societies. Lead scientific exchange, advisory boards, investigator and other external meetings, press conferences, and congress engagement at country level. Collaborate effectively with Regional and Global teams by contributing to overall medical affairs strategy, strongly partnering with local, regional and global clinical development and operations teams. Drive local medical strategy across pre-launch, launch, and post-launch phases. Provide local medical expertise on evidence generation activities including local studies, real-world evidence initiatives, and investigator-initiated research (where permitted). Ensure effective execution of publication plans and scientific communication activities. Lead medical launch readiness for oncology products, including training, scientific materials, and field medical engagement plans. Partner with Market Access and Commercial teams to support value communication and reimbursement-related interactions from a medical perspective, e.g. representing and defining evidence and value of innovation at oral HTA hearings. Support lifecycle management activities including new indications, label updates, and competitive positioning. Work closely with Market Access, Commercial, Regulatory, Safety, and Corporate Affairs teams to ensure aligned and compliant execution of country plans. Provide medical review and approval of non-promotional materials in accordance with local regulations and company policies. Build, lead, and develop the country Medical Affairs team when/if applicable, including Medical advisors and MSLs. Establish medical processes, governance, and ways of working as part of the country build-out. Foster a culture of scientific rigor, compliance, and collaboration. Ensure all medical activities comply with local regulations, national and regional codes, and internal company policies. Represent Medical Affairs in country governance and risk management forums. Required Skills, Experience and Education: Advanced degree required (PhD, or PharmD). Strong background and experience in oncology required. 10+ years’ experience in Medical Affairs with a track record of country leadership. Proven value and benefit assessment experience, with deep understanding of Canadian payer decision-making. Strong stakeholder management and ability to collaborate with internal and external partners. Proven experience supporting oncology product launches in Canada. Strong understanding of the local healthcare system, clinical practice, and regulatory environment. Experience in a biotech and/or in a build-out. Excellent communication skills, both in person and virtual. Proven leadership and people management capabilities; demonstrated success in small but fast growing, entrepreneurial environment. Scientific and solution-orientated mindset and capability to move and execute in a rapidly changing, ambiguous environment. Strong understanding of local healthcare systems, customer dynamics, and reimbursement environments. Willingness to travel nationally and internationally. Bilingual (English/French) preferred. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy . For additional information, please contact privacy@revmed.com . #LI-SH1 #LI-Remote The base pay salary range for this full-time position for candidates working from the location designated on this posting is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working from the location stated on this posting and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training. Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities. Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy . For additional information, please contact privacy@revmed.com . Base Pay Salary Range $196,000 — $245,000 CAD We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message. Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address. If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.