Data & AI Engineer II

CareDx, Inc. is a leading precision medicine solutions company focused on the discovery, development, and commercialization of clinically differentiated, high-value healthcare solutions for transplant patients and caregivers. CareDx offers products, testing services, and digital healthcare solutions along the pre- and post-transplant patient journey, and is the leading provider of genomics-based information for transplant patients.

The Data & AI Engineer II will develop analytical applications, data pipelines, and AI-powered capabilities that support clinical research, statistical analysis, and data-driven decision-making. This role helps transform research workflows, statistical analyses, and machine learning models into reliable, secure, and user-facing software. The engineer will collaborate with data scientists, statisticians, engineers, clinicians, and product stakeholders to productionize analytical workflows, translate R-based analyses into maintainable Python, and deliver applications for internal and external users. The engineer will also contribute to AI-powered features that analyze structured and unstructured data, extract information from documents, synthesize analytical results, and help users interpret scientific and clinical information. Success in this role requires strong software engineering fundamentals, curiosity, and the ability to independently deliver well-defined components and features with support on more complex technical decisions.

Responsibilities:

• Develop and maintain analytical applications using tools and frameworks such as Python, Streamlit, Plotly, Dash, and Django.
• Own the implementation, testing, deployment, and maintenance of well-defined application features and data workflows.
• Productionize statistical models and machine learning workflows developed by data scientists and statisticians.
• Translate and refactor R-based research and analytical workflows into maintainable, tested Python code.
• Build and maintain data pipelines that support clinical data processing, analysis, visualization, and reporting.
• Develop interactive applications that enable data exploration, visualization, and decision support.
• Integrate applications with relational databases, APIs, analytical outputs, documents, and other structured and unstructured data sources.
• Contribute to AI-powered application features using techniques such as structured information extraction, retrieval-augmented generation, tool or function calling, and multi-step workflows.
• Implement validation, grounding, logging, traceability, and human-review mechanisms for AI-generated outputs.
• Collaborate with scientists, clinicians, product stakeholders, and senior engineers to translate requirements into practical technical solutions.
• Participate in technical design discussions and document implementation decisions, assumptions, and tradeoffs.
• Write reliable, readable, and testable code using established engineering patterns and team standards.
• Participate in code reviews and incorporate feedback to improve implementation quality and technical judgment.
• Monitor, debug, and improve application performance and reliability across data, model, AI, and application layers.
• Follow security, privacy, and compliance requirements for sensitive healthcare data, including HIPAA-aligned practices.
• Contribute to shared components, documentation, development tools, and engineering process improvements.
• Communicate progress, risks, dependencies, and technical challenges clearly and proactively.

Qualifications:

• Education: Bachelor’s or master’s degree in Computer Science, Data Science, Engineering, Biostatistics, or a related quantitative field, or equivalent practical experience.
• Experience: 2+ years of experience in data engineering, backend engineering, full-stack development, analytics engineering, or a related role.
• Strong proficiency in Python for data analysis and software development.
• Experience working with statistical analysis, data science, or machine learning workflows.
• Experience transforming prototype, research, or analytical code into maintainable software.
• Experience building analytical applications using Streamlit, Plotly, Dash, or similar technologies.
• Experience developing backend services or web applications using Django, FastAPI, Flask, or a similar framework.
• Experience building and maintaining data pipelines that integrate multiple data sources.
• Familiarity with relational databases, SQL, APIs, and common data formats.
• Experience or demonstrated applied knowledge in at least one modern LLM capability, such as retrieval-augmented generation, structured extraction, tool calling, or agentic workflows.
• Understanding of core production considerations for AI systems, including grounding, hallucination mitigation, output validation, security, latency, cost, and human oversight.
• Experience with version control and collaborative development practices, including Git, branching, pull requests, and code reviews.
• Experience writing automated tests and debugging applications across multiple technical layers.
• Ability to independently deliver well-defined features while seeking guidance when requirements or technical risks are unclear.
• Strong written and verbal communication skills.
• Honest and transparent approach to feedback, collaboration, and accountability.

Preferred Qualifications:

• Experience in healthcare, biotechnology, clinical research, or another regulated environment.
• Experience working with sensitive or protected healthcare data.
• Familiarity with HIPAA-aligned application and data-handling practices.
• Experience with Azure, Databricks, or comparable cloud and data platforms.
• Familiarity with CI/CD practices and automated testing tools such as pytest.
• Experience with pandas, NumPy, scikit-learn, statsmodels, or similar data science libraries.
• Experience deploying or supporting production web applications.
• Experience using modern AI-assisted software development tools, such as Codex or similar coding agents, for development, testing, debugging, and documentation.
• Domain knowledge in biological medicine, healthcare, or clinical data.
• Experience communicating technical work to scientific or clinical audiences.

Additional Details:

Every individual at CareDx has a direct impact on our collective mission to improve the lives of organ transplant patients worldwide. We believe in taking great care of our people, so they take even greater care of our patients.

Our competitive Total Rewards package for US Employees includes:

Competitive base salary and incentive compensation Health and welfare benefits, including a gym reimbursement program 401(k) savings plan match Employee Stock Purchase Plan Pre-tax commuter benefits And more!

In addition, we have a Living Donor Employee Recovery Policy that allows up to 30 days of paid leave annually to a full-time employee who makes the selfless act of donating an organ or bone marrow.

With products that are making a difference in the lives of transplant patients today and a promising pipeline for the future, it’s an exciting time to be part of the CareDx team. Join us in partnering with transplant patients to transform our future together.

CareDx, Inc. is an Equal Opportunity Employer-vets/disabled, and participates in the E-Verify program.

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#LI-Remote

This is the anticipated base salary range for candidates who will work in Brisbane, California. The final salary offered to a successful candidate will be dependent on several factors that may include, but are not limited to, the type and length of experience within the job, the type and length of experience within the industry, education, etc. Base pay is one part of the Total Package that is provided to compensate and recognize employees for their work, and this role may be eligible for additional discretionary bonuses/incentives and restricted stock units. CareDx is a multi-state employer, and this salary range may not reflect positions that work in other states.

San Francisco Bay Area Roles

$133,000 — $166,000 USD

This is the anticipated base salary range in the United States. The final salary offered to a successful candidate will be dependent on several factors that may include, but are not limited to, the type and length of experience within the job, the type and length of experience within the industry, education, etc. Base pay is one part of the Total Package that is provided to compensate and recognize employees for their work, and this role may be eligible for additional discretionary bonuses/incentives and restricted stock units. CareDx is a multi-state employer, and this salary range may not reflect positions that work in other states.

Remote: US only roles

$108,000 — $135,000 USD