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Biogen

Associate Scientific Director, Pharmacometrics

RemoteUnited States only
Published
Role
Research
Experience
Senior
Company size
Mid-size
$167k–$230k/yr
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Open to US only. Set where you work from to check your eligibility.

No BS summary

Quantitative scientist with a PhD and 5+ years in industry pharmacometrics. Must have deep population PK/PD, MIDD, clinical pharmacology, regulatory, and hands-on NONMEM/Monolix/R experience for drug development programs.

Core skills

PK/PD modelingPharmacometrics

Required skills

NONMEMMonolixR

Optional skills

Mechanistic pharmacology modelsSystems pharmacology models

What you'll do

  • Provide pharmacometrics expertise to activities throughout the drug development lifecycle and effectively collaborate with cross functional teams
  • Execute advanced pharmacometrics analyses, with emphasis on PK/PD modeling and simulation and exposure-response analysis for high priority programs
  • Identify opportunities where modeling and simulation can advance the understanding of pharmacokinetics, pharmacodynamics, efficacy and safety
  • Contribute to Model Informed Drug Development (MIDD) activities to support dose selection, regimen optimization and clinical trial design
  • Communicate the pharmacometrics analysis results to program teams to support data-driven decision-making process
  • Mentor and guide Clinical Pharmacology and Pharmacometrics colleagues on pharmacometrics analyses methodologies
  • Serve as a lead author and key contributor for pharmacometrics sections of clinical and regulatory documents
  • Publish in scientific journals and present at internal and external scientific events

What they require

  • PhD in Pharmacology, Pharmacokinetics, Pharmaceutics or a related quantitative discipline.
  • 5+ years of relevant industry experience applying population PK/PD and other advanced quantitative methodologies to decision making
  • Deep and extensive experience with advanced population PK/PD methodology
  • Strong understanding of the clinical pharmacology principles and methodologies and their application in drug development
  • Solid knowledge of the drug development process and regulatory expectations for pharmacometrics analyses
  • Ability to interpret quantitative results and translate analyses into actionable program insights
  • Hands-on experience with pharmacometrics software tools such as NONMEM, Monolix, and R.
  • Preferred: Experience with mechanistic or systems pharmacology models is a plus.
  • You are a quantitative scientist with strong experience applying population PK/PD analysis methodology to drug development questions.
  • You are comfortable working on complex problems, contributing scientific insight to multidisciplinary teams and supporting program-level decision-making through rigorous quantitative analyses.

Benefits

  • Regular employees are eligible to receive both short term and long-term incentives, including cash bonus and equity incentive opportunities, designed to reward recent achievements and recognize your future potential based on individual, business unit and company performance.
  • Medical, Dental, Vision, & Life insurances
  • Fitness & Wellness programs including a fitness reimbursement
  • Short- and Long-Term Disability insurance
  • A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
  • Up to 12 company paid holidays + 3 paid days off for Personal Significance
  • 80 hours of sick time per calendar year
  • Paid Maternity and Parental Leave benefit
  • 401(k) program participation with company matched contributions
  • Employee stock purchase plan
  • Tuition reimbursement of up to $10,000 per calendar year
  • Employee Resource Groups participation
  • We provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact.
  • Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills.

American multinational biotechnology company

BiotechMid-sizebiogen.com/
$167k–$230k/yr